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be careful with generic sinequan if you take antiarrhythmics eg, quinidine, propafenone, flecainide , antifungal medicines eg, fluconazole, terbinafine , carbamazepine, cimetidine, mibefradil, phenothiazines eg, chlorpromazine, thioridazine , or selective serotonin reuptake inhibitors ssris eg, fluoxetine, sertraline because they may increase the risk of generic sinequan s side effects; anticoagulants eg, warfarin , h1 antagonists eg, astemizole, terfenadine , ibutilide, sulfonylureas eg, tolazamide, glipizide , sympathomimetics eg, phenylephrine, pseudoephedrine , or tramadol because the risk of their side effects may be increased by generic sinequan; clonidine, guanadrel, guanethidine, or guanfacine because their effectiveness may be decreased by generic sinequan; maois eg, furazolidone, phenelzine, isocarboxazid because severe toxic effects may occur.